Florence SC is around 36 miles away from North Carolina Border/South of the Border.
The driving time is around 46 minutes (via I-95 S).
For routes and driving directions, see Distancebetweencities.net.
The East Coast's Main Street, Interstate 95 (I-95) serves the entire Northeast Megalopolis, while also serving southeastern cities of Jacksonville and Miami along Florida's east coast.
The highway is an important factor in commerce and tourism, linking scenic New England with the subtropical environs of southern Florida. It passes through more states than any other Interstate highway.
Check out current traffic conditions for I-95 at i95highway.com.
See travel guide to Florence, SC to help plan your next holiday trip at Travel + Leisure.