Not Medical Advice: As per Drugs.com, there were major drug interactions found between oxycodone and some medicines containing guaifenesin. It is still safe to consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.
See drugs that are known to interact with Mucinex DM (dextromethorphan / guaifenesin) and drugs that are known to interact with Oxycodone at Drugs.com.
Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.
Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.
Dextromethorphan and guaifenesin is a combination medicine used to treat cough and chest congestion caused by the common cold, infections, or allergies.
[Oxycodone]https://www.drugs.com/oxycodone.html(https://www.drugs.com/oxycodone.html) is an opioid pain medication. An opioid is sometimes called a narcotic.
Oxycodone is used to treat moderate to severe pain.
The extended-release form of this medicine is for around-the-clock treatment of pain. This form of oxycodone is not for use on an as-needed basis for pain.
The more you know about the medicines you take, the likelier it is that you will use them safely. WebMD gives you these tips for taking medication.